Uchida Y, Akiyoshi T, Goto M, Katsuki T
Department of Anatomy, Saga Medical School.
Fukuoka Igaku Zasshi. 1993 Nov;84(11):457-79.
Mandibular growth of the fetus is a great matter of importance to anatomy, anthropology and also oral and Maxillofacial surgery. The postnatal changes of the mandible that have occurred with growth have been reported by numerous investigators. However, a few researchers have investigated the prenatal growth of the mandible. The purposes of this study were discussed how to change in size and shape of the mandible during the fetal period. The materials consisted of 162 human fetuses from the body length (BL) of 95 mm, to 500 mm. They were divided into four groups: 95-199 mm (BL1, N = 40), 200-299 mm (BL2, N = 76), 300-399 mm (BL3, N = 26), 400-500 mm (BL4, N = 20). All specimens were stored in formalin, and only those free from gross deformation were selected for study. The heads were removed by decapitation at the level of the hyoid bone. The soft standardized radiographs were taken of the frontal, lateral, basal aspects. They were used for tracing and angular and linear measurements (total thirty). The data were used to evaluate the mandibular form by multivariate analysis. They were supported the univariate analysis. The findings leads to the following conclusions: 1) Cluster analysis and principal component analysis were applied to the data to make clear the correlation between 30 variables. Four clusters were constructed at the level ninety similarities in cluster analysis. They were corresponded to four factors were obtained in principal component analysis. 2) The data were subjected to a stepwise discriminant function analysis using the seventeen of original 30 variables. Nine variables, mandibular length (Go-Me), mandibular ramus height (Col-Go), Symphyseal height (Id-Me), mandibular body height (Kr'-beta), gonial angle (< Co2, Go, Me), mental angle (< Id, Pog, Go), gonial width (BGo), alveolar width (BKr'), basal angle of mandible (< RGo, Me, LGo), were selected as the best discriminators. The incidence of correctly classified cases 88.68%. 3) As a result of the first discriminant function of the discriminant analysis and one-way analysis of variance (ANOVA) and t-test, mandibular length (Go-Me), gonial width (BGo), alveolar width (BKr'), Symphyseal height (Id-Me) were longer in tall group that short group (BL4 > BL3 > BL2 > BL1). Therefore, the first discriminant function was accounted for the size factor. 4) In consequence of the second discriminant function of the discriminant analysis and regression analysis, gonial width (BGo) was grown broader than alveolar width (BKr') from BL1 to BL2.(ABSTRACT TRUNCATED AT 400 WORDS)
胎儿下颌骨的生长对解剖学、人类学以及口腔颌面外科都极为重要。众多研究者已报道了下颌骨在出生后的生长变化。然而,仅有少数研究者对下颌骨的产前生长进行过研究。本研究的目的是探讨胎儿期下颌骨的大小和形状是如何变化的。研究材料包括162例人类胎儿,体长从95毫米至500毫米。它们被分为四组:95 - 199毫米(BL1,N = 40),200 - 299毫米(BL2,N = 76),300 - 399毫米(BL3,N = 26),400 - 500毫米(BL4,N = 20)。所有标本均保存在福尔马林中,仅选择那些没有明显变形的用于研究。通过在舌骨水平断头来取下头部。拍摄了正面、侧面和底面的软组织标准化X线片。用于进行描绘以及角度和线性测量(共30项)。这些数据通过多变量分析来评估下颌骨形态,并得到单变量分析的支持。研究结果得出以下结论:1)对数据应用聚类分析和主成分分析以明确30个变量之间的相关性。在聚类分析中,在相似度为90%的水平构建了四个聚类。它们与主成分分析中获得的四个因素相对应。2)使用原始30个变量中的17个对数据进行逐步判别函数分析。九个变量,下颌骨长度(Go - Me)、下颌支高度(Col - Go)、颏部高度(Id - Me)、下颌体高度(Kr' - beta)、下颌角(< Co2,Go,Me)、颏角(< Id,Pog,Go)、下颌角宽度(BGo)、牙槽宽度(BKr')、下颌骨基底角(< RGo,Me,LGo),被选为最佳判别指标。正确分类病例的发生率为88.68%。3)作为判别分析的第一个判别函数以及单因素方差分析(ANOVA)和t检验的结果,高体长组(BL4 > BL3 > BL2 > BL1)的下颌骨长度(Go - Me)、下颌角宽度(BGo)、牙槽宽度(BKr')、颏部高度(Id - Me)比低体长组更长。因此,第一个判别函数代表大小因素。4)作为判别分析的第二个判别函数以及回归分析的结果,从BL1到BL2,下颌角宽度(BGo)比牙槽宽度(BKr')增长得更宽。(摘要截断于400字)