Skriabin G K, Ganbarov Kh G, Golovleva L A, Chervin I I, Adanin V M
Mikrobiologiia. 1976 Nov-Dec;45(6):951-4.
Microbiological oxidation of xylenes was studied with Pseudomonas aeruginosa, strain 7. The culture grows on m-xylene and, at a lower rate, on p-xylene, but does not grow on o-xylene though partly oxidizes it. Pathways of primary enzymatic oxidation of xylenes by the culture were established. Oxidation of m-xylene follows the pathway described earlier but methylsalicylic acid formed is not accumulated in the medium and is transformed into 3-methylcatechol. The aromatic ring is splitted according to the meta pathway. It has been demonstrated for the first time that o-xylene is oxidized to o-hydroxymethylbenzoic acid.
利用铜绿假单胞菌7株研究了二甲苯的微生物氧化。该培养物能在间二甲苯上生长，对二甲苯生长速率较低，但不能在邻二甲苯上生长，不过能部分氧化邻二甲苯。确定了该培养物对二甲苯进行初级酶促氧化的途径。间二甲苯的氧化遵循先前描述的途径，但形成的甲基水杨酸不会在培养基中积累，而是转化为3 - 甲基儿茶酚。芳香环按照间位途径裂解。首次证明邻二甲苯被氧化为邻羟基甲基苯甲酸。
