Tian Y, Luo X, Li H, Zhang D
Hua Xi Yi Ke Da Xue Xue Bao. 1993 Sep;24(3):324-7.
Twenty-six patients undergoing right cardiac catheterization were examined by pulsed doppler echocardiography (PDE), spectrum analysis of the shape of flow velocity curve of the pulmonary arteria during systole was made. Pulmonary arterial pressure (PAP) was qualitatively and qualitatively evaluated by right ventricular systolic time interval (RSTI) derived from pulmonary doppler blood flow velocity pattern. The correlation between PAP and the values of RSTI was evaluated, multiple stepwise regression analysis was performed. The pulmonary flow pattern and the values of RSTI measured from right ventricular outflow tract (RVOT) and main pulmonary artery (MPA) were compared. The results showed that: 1. Qualitative evaluation of PAP: (1) the triangular configuration of the pulmonary flow pattern was the feature of the pulmonary ejection flow in pulmonary hypertension (PH). (2) AT < 100ms AT/ET < 0.30 and PEP/AT > 1.1 indicated PH (PAMP > or = 2.7 kPa, AT < 100 ms, sensitivity 92.3%, specificity 100%). 2. Quantitative evaluation of PAP: (1) simple regression analysis: AT, AT/PEP especially AT showed a good inverse correlation with PAP, which was improved when a logarithmic function was applied, but not improved by the square root of heart rate. The liner regression equation and the correlation coefficient were: log PASP = -6.3617 AT +2.825 (r = -0.7925, P < 0.001); log PADP = -0.4569 AT +74.182 (r = -0.8513, P < 0.001); log PAMP = -0.0073 AT +2.198 (r = -0.8635, P < 0.001). (2) multiple stepwise regression analysis: the stepwise analysis of six parameters (PEP, ET, AT, AT/ET, AT/PEP, square root of R-R) showed that AT, PEP were the best parameters correlated with PAP.(ABSTRACT TRUNCATED AT 250 WORDS)
对26例行右心导管检查的患者进行了脉冲多普勒超声心动图(PDE)检查,对肺动脉收缩期血流速度曲线形态进行频谱分析。通过肺动脉多普勒血流速度模式得出的右心室收缩时间间期(RSTI)对肺动脉压(PAP)进行定性和定量评估。评估PAP与RSTI值之间的相关性,并进行多元逐步回归分析。比较了右心室流出道(RVOT)和主肺动脉(MPA)的肺血流模式及RSTI值。结果显示:1. PAP的定性评估:(1)肺血流模式的三角形形态是肺动脉高压(PH)时肺射血血流的特征。(2)AT<100ms、AT/ET<0.30及PEP/AT>1.1提示PH(PAMP≥2.7kPa,AT<100ms,敏感性92.3%,特异性100%)。2. PAP的定量评估:(1)简单回归分析:AT、AT/PEP尤其是AT与PAP呈良好的负相关,应用对数函数时相关性增强,但心率平方根不能改善相关性。线性回归方程及相关系数为:log PASP=-6.3617AT+2.825(r=-0.7925,P<0.001);log PADP=-0.4569AT+74.182(r=-0.8513,P<0.001);log PAMP=-0.0073AT+2.198(r=-0.8635,P<0.001)。(2)多元逐步回归分析:对六个参数(PEP、ET、AT、AT/ET、AT/PEP、R-R平方根)进行逐步分析显示,AT、PEP是与PAP相关性最好的参数。(摘要截选至250词)