Paoli G, Borgognini Tarli S M, Klír P, Strouhal E, Tofanelli S, Del Santo Valli M T, Pavelcová B
Dipartimento di Scienze, Università di Pisa, Italy.
Am J Phys Anthropol. 1993 Nov;92(3):263-72. doi: 10.1002/ajpa.1330920304.
A paleoserological study of human remains from the Christian cemeteries of Sayala (Lower Nubia, 6th-11th centuries A.D.) was carried out by applying two techniques (absorption-elution and haemagglutination-inhibition), on two types of substratum (bones and hair), in separate laboratories (Pisa and Prague). The aim of research was to evaluate the degree of repeatability of the results and the reliability of the final paleoserological diagnoses. The results indicated different degrees of repeatability depending on the differential sensitivity of the two techniques and on the nature of the substratum. The frequencies of concordant and discordant final diagnoses within and between the two laboratories and by the two methods were significantly different from those expected under the conditions of random distribution, indicating a consistency in results from different laboratories and methods. The reliability of the resulting gene and phenotype distributions is also supported by their consistency both with the theoretical Hardy-Weinberg equilibrium and with the present distribution of the ABO gene frequencies in Egyptian, Sudanese, and Nubian populations.
通过在两个独立实验室（比萨和布拉格）对两种基质（骨骼和毛发）应用两种技术（吸收-洗脱和血凝抑制），对来自赛亚拉基督教墓地（下努比亚，公元6至11世纪）的人类遗骸进行了古血清学研究。研究目的是评估结果的可重复性程度以及最终古血清学诊断的可靠性。结果表明，根据两种技术的不同敏感性和基质的性质，可重复性程度有所不同。两个实验室内部以及两个实验室之间通过两种方法得出的最终诊断结果一致和不一致的频率，与随机分布条件下预期的频率显著不同，这表明不同实验室和方法的结果具有一致性。所得基因和表型分布的可靠性还得到了它们与理论上的哈迪-温伯格平衡以及埃及、苏丹和努比亚人群中ABO基因频率的当前分布相一致的支持。
