无色氨酸氨基酸混合物对雌性大鼠性行为的影响未呈现改变。

Failure of a tryptophan-free amino acid mixture to modify sexual behavior in the female rat.

作者信息

Benedetti F, Moja E A

机构信息

Chair of Medical Psychology II, Medical School, University of Milano, Italy.

出版信息

Physiol Behav. 1993 Dec;54(6):1235-7. doi: 10.1016/0031-9384(93)90354-i.

DOI:10.1016/0031-9384(93)90354-i

PMID:8295969

Abstract

Female Wistar rats, weekly injected with estradiol valerate after ovariectomy, were trained to cause a sexual contact with a potent male by operating a lever. Contact-response latencies, which vary according to the nature of the sexual contact, were measured as an index of the female's sexual motivation. In these experimental conditions the administration of a tryptophan-free amino acid mixture, which has been proved to decrease brain serotonin and to enhance male mounting behavior, failed to modify the sexual motivation of the female rats.

摘要

对卵巢切除术后每周注射戊酸雌二醇的雌性Wistar大鼠进行训练，使其通过操作杠杆与强壮的雄性大鼠进行性接触。根据性接触的性质而变化的接触反应潜伏期被作为雌性大鼠性动机的指标进行测量。在这些实验条件下，给予一种不含色氨酸的氨基酸混合物，该混合物已被证明可降低脑血清素并增强雄性大鼠的骑跨行为，但未能改变雌性大鼠的性动机。