[在超低磁场强度磁共振断层扫描中使用钆喷酸葡胺（Gd-DTPA）对脑和脊髓肿瘤进行对比增强]

[The contrast enhancement of brain and spinal cord tumors using Gd-DTPA in magnetic resonance tomography with an extra-low magnetic-field intensity].

作者信息

Kornienko V N, Pronin I N, Turkin A M, Fadeeva L M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1993 Oct-Dec(4):13-7.

Abstract

The contrasting agent Gd-DTPA (Magnevist, Schering AG, Germany) was tested when used in magnetic resonance tomography using extra-low (0.04 T) magnetic field intensity in 68 patients with various brain and spine tumors. The agent was injected intravenously in a dose of 0.1 mmol/kg. No complications were found. The tests showed its high efficiency in the diagnosis of brain neoplasms (particularly in malignant intracerebral disorders, meningiomas and neurinomas). Benign astrocytomas induced no noticeable signal intensification on post-contrasting T1-weighed tomograms. In all cases of spinal tumors, the application of Gd-DTPA could specify the extent of tumor invasions, the presence of cysts and identify accessory tumor nodes in one case.

摘要

在68例患有各种脑和脊柱肿瘤的患者中，对造影剂钆喷酸葡胺（马根维显，德国先灵公司）在超低（0.04T）磁场强度的磁共振断层扫描中的应用进行了测试。以0.1mmol/kg的剂量静脉注射该造影剂。未发现并发症。测试表明其在脑肿瘤诊断中具有高效性（尤其在恶性脑内疾病、脑膜瘤和神经鞘瘤中）。良性星形细胞瘤在增强后的T1加权断层扫描上未引起明显的信号增强。在所有脊柱肿瘤病例中，钆喷酸葡胺的应用可以明确肿瘤侵犯范围、囊肿的存在情况，并且在1例中识别出附属肿瘤结节。