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伦敦南部躯体化研究。I:纵向病程及早期生活经历的影响。

The South London Somatisation Study. I: Longitudinal course and the influence of early life experiences.

作者信息

Craig T K, Boardman A P, Mills K, Daly-Jones O, Drake H

机构信息

St Thomas' Hospital, London.

出版信息

Br J Psychiatry. 1993 Nov;163:579-88. doi: 10.1192/bjp.163.5.579.

Abstract

In a two-year longitudinal study, a two-stage screening procedure was used to identify subjects in primary care with emotional disorder presenting with a recent onset of physical symptoms and a comparison sample of patients presenting with physical symptoms only. Somatisers (n = 44) were defined as subjects who had an emotional disorder but who presented with physical symptoms that could not be attributed to organic disease. The course and outcome of these conditions were compared with those of pure emotional disorder (n = 11), pure physical disorder (n = 90) and 'mixed' conditions (n = 39). The physical symptoms of somatisers were less likely to improve and lagged behind those of the other groups, and 16 of these acute somatisers went on to develop chronic somatoform disorders. Among somatisers, changes in physical symptom levels throughout the follow-up closely mirrored changes in emotional arousal. Emotionally disordered subjects reported more instances of parental lack of care, but somatisers were also more likely than other groups to report parental physical illness and to have had more physical illness themselves in childhood. A logistic regression suggests that adult somatisation is best modelled by parental lack of care followed by childhood illness.

摘要

在一项为期两年的纵向研究中,采用两阶段筛查程序来识别初级保健中患有情绪障碍且近期出现躯体症状的受试者,以及仅表现出躯体症状的患者对照样本。躯体化者(n = 44)被定义为患有情绪障碍但出现无法归因于器质性疾病的躯体症状的受试者。将这些情况的病程和结果与纯情绪障碍(n = 11)、纯躯体障碍(n = 90)和“混合”情况(n = 39)的病程和结果进行比较。躯体化者的躯体症状改善的可能性较小,且落后于其他组,这些急性躯体化者中有16人后来发展为慢性躯体形式障碍。在躯体化者中,随访期间躯体症状水平的变化与情绪唤醒的变化密切相关。情绪障碍受试者报告父母缺乏关爱情况的实例更多,但躯体化者比其他组更有可能报告父母有躯体疾病,且自己在童年时期患过更多躯体疾病。逻辑回归分析表明,成人躯体化的最佳模型是父母缺乏关爱,其次是童年疾病。

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