Hoszowski K, Gawron J, Korczyk P, Grabski T, Jedrzejewska-Korczyk J, Markiewicz J, Lorenc R S
II Oddziału Wewnetrznego, Warszawie.
Pol Tyg Lek. 1993 Nov;48 Suppl 3:31-5.
Vertebral fractures are the one typically seen in osteoporosis. An incidence of vertebral body fractures and risk factors for osteoporosis were analysed in the retrospective population based epidemiological study. Population sample included 607 Warsaw inhabitants aged between 50 and 80 years (301 women and 306 men divided into age groups of 5 years, including approx. 50 subjects each). Vertebral body fractures were diagnosed on thoraco-lumbar spine X-rays made in the lateral projection. Risk factors for osteoporosis were analysed with the aid of an questionnaire. Bone mineral density was measured with dual energy X-ray absorptiometry and single photon absorptiometry in about 1/3 of the examined women. The prevalence of vertebral osteoporosis was high in both women (20.5%) and in men (27.8%). Low dietary calcium intake (below 800 mg daily) and low serum vitamin D levels (250HD less than 11 micrograms/ml) were characteristic for about 90% of the examined population. In osteoporotic subjects the following risk factors were significantly more frequent: age (p < 0.01), tobacco smoking (p < 0.001), low physical activity (p < 0.05), long-term immobilization (p < 0.01). Densitometry showed significantly lower bone mineral density in both women with vertebral fractures (p < 0.01) and low serum vitamin D levels (p < 0.05). Osteoporotic vertebral fractures were diagnosed more frequently in women with early menopause (p < 0.001). In the examined population there is a ligh prevalence of vertebral osteoporosis (predominating in mean) and risk factors.
椎体骨折是骨质疏松症中常见的一种。在一项基于回顾性人群的流行病学研究中,分析了椎体骨折的发生率及骨质疏松症的危险因素。人群样本包括607名年龄在50至80岁之间的华沙居民(301名女性和306名男性,按5岁年龄组划分,每组约50人)。通过胸腰椎侧位X线片诊断椎体骨折。借助问卷分析骨质疏松症的危险因素。约三分之一接受检查的女性通过双能X线吸收法和单光子吸收法测量骨密度。女性(20.5%)和男性(27.8%)的椎体骨质疏松症患病率都很高。约90%的受检人群具有低膳食钙摄入量(每日低于800毫克)和低血清维生素D水平(250HD低于11微克/毫升)的特征。在骨质疏松症患者中,以下危险因素更为常见:年龄(p<0.01)、吸烟(p<0.001)、低体力活动(p<0.05)、长期制动(p<0.01)。骨密度测量显示,椎体骨折女性和血清维生素D水平低的女性骨密度均显著降低(p<0.01和p<0.05)。绝经早的女性更常被诊断为骨质疏松性椎体骨折(p<0.001)。在受检人群中,椎体骨质疏松症(以平均值为主)和危险因素的患病率较高。