Leyden J J, Aly R
Hospital of the University of Pennsylvania, Department of Dermatology, Philadelphia.
Semin Dermatol. 1993 Dec;12(4):280-4.
Tinea pedis is a term used to encompass several clinically distinctive infections of the skin of the foot. Dermatophytic fungi are primarily responsible for these infections. Several nondermatophytes have been implicated in some patients, particularly for nail infections. The major clinical variants are (1) interdigital infections in which dermatophytes initiate the process by damaging the stratum corneum while the subsequent maceration and leukokeratosis results from overgrowth of bacteria such as Micrococcus sedantarius, Brevibacterium epidermidis, Corynebacterium minutissimum and gram-negative organisms; (2) plantar mocasin type of hyperkeratosis due to T rubrum and found primarily in those with an atopic background; (3) vesiculo-bullous infections in the arch and side of the foot due to an immune response of delayed hypersensitivity to T mentagrophytes.
足癣是一个用于涵盖足部皮肤几种临床上有明显特征的感染的术语。皮肤癣菌是这些感染的主要致病菌。一些非皮肤癣菌也与部分患者的感染有关，尤其是指甲感染。主要的临床变种有：（1）指间感染，皮肤癣菌通过破坏角质层引发这一过程，而随后的浸渍和白色角化病是由诸如定居微球菌、表皮短杆菌、极小棒状杆菌和革兰氏阴性菌等细菌过度生长导致的；（2）由红色毛癣菌引起的足底拖鞋型角化过度，主要见于有特应性背景的人群；（3）足弓和足部侧面的水疱大疱性感染，是由于对须癣毛癣菌的迟发型超敏反应的免疫反应所致。
