Fukui T, Hasegawa Y, Seriyama S, Takeuchi T, Sugita K, Tsukagoshi H
Department of Neurology, Showa University School of Medicine, Tokyo, Japan.
Can J Neurol Sci. 1993 Nov;20(4):324-8.
Four patients presented with hemiballism-hemichorea as a clinical manifestation of white matter ischemia. These patients illustrate "positive" motor phenomena rather than limb weakness as a consequence of cerebral ischemia. In each patient, the involuntary movements disappeared following worsening of paresis. Subcortical white matter infarction in three patients and hemodynamic hypo-perfusion in the cerebral hemisphere contralateral to dyskinetic movements were possible causes. Neuroradiologically, none had pathological changes in the vicinity of the subthalamic nucleus. We presume from these observations that ischemia of the subcortical white matter, without involvement of the basal ganglia or the subthalamic nucleus, may cause hemiballism-hemichorea.
4例患者以偏侧投掷-舞蹈症为白质缺血的临床表现。这些患者表现出“阳性”运动现象,而非脑缺血导致的肢体无力。在每例患者中,随着轻瘫加重,不自主运动消失。3例患者存在皮质下白质梗死,且运动障碍对侧大脑半球存在血流动力学灌注不足,这可能是病因。神经放射学检查显示,无一例患者丘脑底核附近有病理改变。基于这些观察结果,我们推测皮质下白质缺血,若不累及基底节或丘脑底核,可能会导致偏侧投掷-舞蹈症。