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心脏手术期间用于心肌保护的逆行灌注心脏停搏液的效果。

Results with retrograde delivery of cardioplegia for myocardial protection during cardiac surgery.

作者信息

Emery R W, Arom K V

机构信息

Minneapolis Heart Institute, MN 55407.

出版信息

J Cardiovasc Surg (Torino). 1993 Apr;34(2):123-7.

PMID:8320245
Abstract

From November 19, 1990 through November 18, 1991 242 consecutive patients underwent cardioplegic arrest using retrograde delivery of crystalloid cardioplegia via blind transatrial cannulation of the coronary sinus. Of these procedures 196 (81%) were coronary artery bypass procedures. The overall operative mortality was 0.4%. Ten patients (3%) had enzyme and/or ECG criteria for myocardial damage in the peri-operative period and there was one deep sternal wound infection (0.4%). Two patients required VAD assistance post-operative, one following Protamine reaction (LVAD) and one following RV infarction and failed PTCA (RVAD). Both survived. Ninety-seven patients (40%) developed supraventricular arrhythmias and 20% required temporary pacing post-op for less than 6 hours. These results indicate the safety and effectiveness of retrograde delivery of intermittent crystalloid cardioplegia solution in general cardiac surgery.

摘要

从1990年11月19日至1991年11月18日,242例连续患者通过经冠状静脉窦盲穿房间隔逆行输注晶体心脏停搏液进行心脏停搏。其中196例(81%)手术为冠状动脉搭桥手术。总体手术死亡率为0.4%。10例患者(3%)在围手术期有心肌损伤的酶学和/或心电图标准,有1例深部胸骨伤口感染(0.4%)。2例患者术后需要心室辅助装置支持,1例因鱼精蛋白反应(左心室辅助装置),1例因右心室梗死和经皮冠状动脉腔内血管成形术失败(右心室辅助装置)。两人均存活。97例患者(40%)发生室上性心律失常,20%患者术后需要临时起搏少于6小时。这些结果表明,在一般心脏手术中,间歇性晶体心脏停搏液逆行输注是安全有效的。

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