迷走神经刺激频率和心房刺激间期对房室传导时间的联合影响。

The combined influence of the stimulus frequency of the vagal nerves and the atrial stimulus interval on the atrioventricular conduction time.

作者信息

de Beer E L, Boom H B, Naafs B

出版信息

Cardiovasc Res. 1977 Jan;11(1):47-54. doi: 10.1093/cvr/11.1.47.

DOI:10.1093/cvr/11.1.47

Abstract

The way in which the A-V node adapts its conduction time to stepwise alterations of atrial stimulation rates was studied under different conditions of vagal nerve activity (open chest, anaesthetised rabbit). Increase of stimulation rate induced oscillatory adaptation to a longer conduction time. Decrease caused shorter conduction times without oscillation. The time constant did not differ. Oscillation amplitude and time constants were markedly influenced by vagal activity. The observed phenomena can be explained on the basis of a time and voltage dependent K+ conductance.

摘要

在迷走神经活动的不同条件下（开胸、麻醉兔），研究了房室结将其传导时间适应心房刺激率逐步变化的方式。刺激率增加导致振荡性适应至更长的传导时间。刺激率降低导致传导时间缩短且无振荡。时间常数无差异。振荡幅度和时间常数受迷走神经活动的显著影响。所观察到的现象可基于时间和电压依赖性钾电导来解释。