Mergoni M, Saccani A, Salvadori A, Grattagliano C, Pagliari S, Bortone L
I Servizio di Anestesia e Rianimazione, Ospedale Maggiore, Parma.
Minerva Anestesiol. 1993 Apr;59(4):187-92.
Impairment of the state of consciousness is an important contributing factor in the onset of respiratory tract infections; in this study the data were collected prospectively to investigate the incidence and clinical implications of pneumonia in a population of head injured patients. The study was conducted on all patients treated at our centre throughout 1990. The incidence of pneumonia in the head injured was 10.8% versus 7.3% in the rest of the patients. Mortality in the group with pneumonia was not significantly different from the group without pneumonia. The average time of onset was on the fifth day from admission. The lung injury score (LIS) on the sixth day, the time on artificial ventilation and the length of stay in intensive care were significantly greater in those with pneumonia (1.18, 14.6 days and 21.9 days versus 0.8, 4.2 days and 12.9 days respectively). Staphylococcus was the single most frequently isolated germ. Our study concludes that pneumonia represents a relatively frequent and early complication in patients with head injury, and it is associated with prolonged artificial ventilation and longer staying in ICU.
意识状态受损是呼吸道感染发病的一个重要促成因素;在本研究中,前瞻性收集数据以调查颅脑损伤患者群体中肺炎的发病率及临床意义。该研究针对1990年在我们中心接受治疗的所有患者开展。颅脑损伤患者中肺炎的发病率为10.8%,而其他患者为7.3%。肺炎组的死亡率与无肺炎组无显著差异。发病的平均时间为入院后第五天。肺炎患者第六天的肺损伤评分(LIS)、使用人工通气的时间以及在重症监护室的住院时间显著更长(分别为1.18、14.6天和21.9天,而无肺炎患者分别为0.8、4.2天和12.9天)。葡萄球菌是最常分离出的单一病菌。我们的研究得出结论,肺炎是颅脑损伤患者中相对常见且早期出现的并发症,并且与人工通气时间延长和在重症监护病房停留时间延长相关。