Kotz R
Universitätsklinik für Orthopädie, Wien.
Orthopade. 1993 Jun;22(3):160-6.
In the Department of Orthopedics at the University of Vienna, tumor endoprostheses have been implanted after resections of tumors of the upper extremities since 1974 and of the knee joint since 1976. For replacement of the humerus after tumor resection, a system of modular tumor endoprostheses was developed very early. Initially, it was ceramic and later on made of titanium alloys, which were also implanted in combination with custom-made prostheses with cementless stem-plate fixation in 57 patients until February 1990. In 43 of these patients (75.4%) adequate resection (2 radical and 41 wide) had been performed. Of 49 patients with a follow-up period of at least 24 months, 36 patients had a mean disease-free survival time of 106.1 months. Between 1976 and 1981, 16 custom-made endoprostheses were used after tumor resection of the knee joint. Since 1982 we have used a modular system of tumor endoprostheses suitable for replacement of the proximal and distal femur, proximal tibia, total femur and total knee joint. Of 75 patients who had been operated on up to February 1990, 67 patients (89.3%) had undergone adequate resection (2 radical and 65 wide). Out of 32 of these patients, 24 (75%) exhibited a disease-free survival time of at least 24 months (mean 48.2 months). Out of 213 patients with resection/reconstruction (160 endoprostheses), 77.8% had a survival time of at least 24 months, a results which is considerably better than in 146 patients with amputation in which case the respective value was 69.4%.(ABSTRACT TRUNCATED AT 250 WORDS)
自1974年起,维也纳大学骨科就开始在切除上肢肿瘤后植入肿瘤假体,自1976年起在膝关节肿瘤切除后植入。肿瘤切除后用于肱骨置换的模块化肿瘤假体系统很早就已开发出来。最初是陶瓷材质,后来采用钛合金材质,截至1990年2月,已有57例患者植入了这种假体,并结合定制假体采用无水泥柄板固定。其中43例患者(75.4%)进行了充分切除(2例根治性切除和41例广泛切除)。在49例随访期至少24个月的患者中,36例患者的平均无病生存期为106.1个月。1976年至1981年期间,膝关节肿瘤切除后使用了16个定制假体。自1982年以来,我们采用了一种模块化肿瘤假体系统,适用于股骨近端和远端、胫骨近端、全股骨和全膝关节的置换。截至1990年2月,在接受手术的75例患者中,67例患者(89.3%)进行了充分切除(2例根治性切除和65例广泛切除)。在这些患者中的32例中,24例(75%)的无病生存期至少为24个月(平均48.2个月)。在213例接受切除/重建手术的患者(160例植入假体)中,77.8%的患者生存期至少为24个月,这一结果明显优于146例接受截肢手术的患者,后者相应比例为69.4%。(摘要截取自250字)