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急性主动脉夹层导致结肠梗死时的肌酸激酶同工酶模式。病例报告。

Creatine-kinase isoenzyme pattern in colonic infarction consequent to acute aortic dissection. A case report.

作者信息

Cavaliere F, Martinelli L, Guarneri S, Morelli M, Possati G F, Schiavello R

机构信息

Department of Anesthesiology and Resuscitation, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

J Cardiovasc Surg (Torino). 1993 Jun;34(3):263-5.

PMID:8344980
Abstract

Bowel infarction can complicate acute aortic dissection (AAD); in that case early diagnosis, which decreases the high mortality, is often difficult. We report the case of one patient who underwent surgery for AAD and developed a colonic infarction, which was clinically manifest on the 4th postoperative day. However, bowel ischemia was suspected already 48 hours after surgery, on the basis of the suggestive CK pattern and the absence of myoglobin in plasma. Total CK activity reached the highest level only 48 hours after surgery (92,800 U/l); the peak was coincident with LDH, which increased proportionally less; CK-MM constituted 100% of total CK activity. The absence of myoglobin in plasma excluded the presence of rhabdomyolysis. We conclude that such laboratory findings suggest the occurrence of severe bowel ischemia.

摘要

肠梗死可使急性主动脉夹层(AAD)复杂化;在这种情况下,早期诊断往往很困难,而早期诊断可降低高死亡率。我们报告了一例接受AAD手术并发生结肠梗死的患者,该梗死在术后第4天出现临床症状。然而,基于提示性的肌酸激酶(CK)模式以及血浆中肌红蛋白的缺乏,术后48小时就怀疑有肠缺血。总CK活性仅在术后48小时达到最高水平(92,800 U/l);峰值与乳酸脱氢酶(LDH)一致,LDH升高比例较小;CK-MM占总CK活性的100%。血浆中肌红蛋白的缺乏排除了横纹肌溶解的存在。我们得出结论,这些实验室检查结果提示发生了严重的肠缺血。

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