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使用人蛋白焊料对犬输尿管进行体外发色团增强激光焊接:腹腔镜组织焊接的初步步骤。

Chromophore enhanced laser welding of canine ureters in vitro using a human protein solder: a preliminary step for laparoscopic tissue welding.

作者信息

Poppas D, Sutaria P, Sosa R E, Mininberg D, Schlossberg S

机构信息

Department of Urology, New York Hospital-Cornell Medical Center, New York City 10021.

出版信息

J Urol. 1993 Sep;150(3):1052-5. doi: 10.1016/s0022-5347(17)35684-7.

DOI:10.1016/s0022-5347(17)35684-7
PMID:8345583
Abstract

Laser welding of the genitourinary tract has the potential advantage of forming an immediate watertight seal. It may obviate the need for sutures, eliminate the inherent lithogenic reaction to suture, and potentially improve healing. In the current study we employed a KTP-532 laser in vitro to weld canine ureters. Ureters were transected over a stent and immediately repaired using the KTP-532 laser (power density 7.14 W/cm.2, spot size = 0.5 cm.) alone or in combination with different tissue solders. Solders consisted of 40% human albumin alone or with the addition of iron oxide or fluorescein as light absorbing dyes (chromophores). Following the repairs, intraluminal bursting strength and the total energy required to complete the repairs were measured. The KTP laser alone was not able to achieve a satisfactory repair. Successful ureteral repairs were achieved in all solder groups while maintaining ureteral continuity at supraphysiologic pressures.

摘要

泌尿生殖道的激光焊接具有形成即时水密密封的潜在优势。它可能无需缝合,消除对缝合线固有的致石反应,并有可能改善愈合情况。在当前研究中,我们在体外使用KTP - 532激光焊接犬输尿管。输尿管在支架上横断后,立即单独使用KTP - 532激光(功率密度7.14 W/cm²,光斑大小 = 0.5 cm)或与不同的组织焊料联合进行修复。焊料由单独的40%人白蛋白组成,或添加氧化铁或荧光素作为光吸收染料(发色团)。修复后,测量腔内破裂强度以及完成修复所需的总能量。单独使用KTP激光无法实现令人满意的修复。在所有焊料组中均成功实现了输尿管修复,同时在超生理压力下保持了输尿管的连续性。

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