Vestergaard H, Laurberg P
Medicinsk endokrinologisk afdeling, Arhus Kommunehospital, Amtssygehus.
Ugeskr Laeger. 1993 Aug 2;155(31):2403-5.
Radioiodine therapy is often employed for treatment of patients with relapse of hyperthyroidism due to Graves' disease, after previous thyroid surgery. Little is known about the outcome of this treatment compared to patients with no previous surgery. A total of 20 patients, who had received surgical treatment for Graves' hyperthyroidism 1-46 years previously and with relapse of hyperthyroidism, and 25 patients with hyperthyroidism due to Graves' disease and no previous thyroid surgery were treated with radioiodine, following the same protocol. Early after treatment the previously operated patients showed a higher sensitivity to radioiodine, with more cases of early hypothyroidism than non-operated patients. However, after 50 months of follow-up the outcome was identical. The results indicate that frequent assessment is necessary after radioiodine treatment of patients with previous thyroid surgery, since some patients develop early hypothyroidism.
放射性碘疗法常用于治疗先前接受过甲状腺手术、因格雷夫斯病导致甲亢复发的患者。与未接受过手术的患者相比，这种治疗的效果鲜为人知。共有20例患者，他们在1 - 46年前接受过格雷夫斯甲亢的手术治疗且甲亢复发，以及25例因格雷夫斯病导致甲亢且未接受过甲状腺手术的患者，按照相同方案接受了放射性碘治疗。治疗后早期，先前接受过手术的患者对放射性碘表现出更高的敏感性，早期甲状腺功能减退的病例比未接受手术的患者更多。然而，经过50个月的随访，结果是相同的。结果表明，对先前接受过甲状腺手术的患者进行放射性碘治疗后，有必要进行频繁评估，因为一些患者会出现早期甲状腺功能减退。
