Yost J H, Spencer-Green G, Krant J D
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
J Rheumatol. 1993 Jun;20(6):1064-5.
Neurologic manifestations of Paget's disease of bone are primarily a result of mechanical compression on cranial nerves, spinal cord and roots. Less recognized is a myelopathy from "vascular steal" to highly vascularized and hypermetabolic pagetic bone. We describe a case of presumed ischemic myelitis in a patient with Paget's disease and aortic stenosis that was rapidly reversed with subcutaneous calcitonin and intravenous dexamethasone.
骨Paget病的神经系统表现主要是由于对颅神经、脊髓和神经根的机械性压迫所致。较少被认识的是一种因“盗血”至高度血管化和代谢亢进的Paget骨而导致的脊髓病。我们描述了一例患有Paget病和主动脉狭窄的患者发生疑似缺血性脊髓炎的病例,该病例经皮下降钙素和静脉注射地塞米松治疗后迅速好转。