Sironi S, De Cobelli F, Scarfone G, Colombo E, Bolis G, Ferrari A, DelMaschio A
Department of Radiology, Scientific Institute S. Raffaele, Milan, Italy.
Radiology. 1993 Sep;188(3):797-801. doi: 10.1148/radiology.188.3.8351350.
The accuracy of nonenhanced spin-echo (SE) T2-weighted and contrast material-enhanced SE T1-weighted magnetic resonance (MR) imaging in assessing the degree of local tumor invasion was determined prospectively in 53 consecutive patients with clinically established early-stage carcinoma of the cervix. With a 0.5-T superconducting unit, pulse sequences of 2,000/90 (repetition time msec/echo time msec) for T2-weighted images and 500/20 for T1-weighted images were used. In all cases, findings of the two MR imaging techniques were compared with results of histologic examination of surgical specimens. Tumor infiltration into the surrounding structures was classified as partial stromal, complete stromal, or parametrial. Tumor-cervical stroma and tumor-parametrium contrast-to-noise ratios (C/Ns) were higher (P < .05) at nonenhanced T2-weighted than at enhanced T1-weighted than at enhanced T1-weighted imaging. In determining the depth of invasion, the overall accuracy was 85% for nonenhanced T2-weighted and 57% (P < .05) for enhanced T1-weighted imaging. With conventional SE sequences, nonenhanced T2-weighted MR imaging is superior to contrast-enhanced T1-weighted MR imaging in determining the degree of invasiveness in clinical early-stage cervical tumors.
对53例临床确诊为早期宫颈癌的连续患者进行前瞻性研究，以确定非增强自旋回波（SE）T2加权和对比剂增强SE T1加权磁共振（MR）成像在评估局部肿瘤浸润程度方面的准确性。使用0.5-T超导设备，T2加权图像采用2000/90（重复时间毫秒/回波时间毫秒）的脉冲序列，T1加权图像采用500/20的脉冲序列。在所有病例中，将两种MR成像技术的结果与手术标本的组织学检查结果进行比较。肿瘤向周围结构的浸润分为部分间质浸润、完全间质浸润或宫旁浸润。非增强T2加权成像时肿瘤-宫颈间质和肿瘤-宫旁的对比噪声比（C/Ns）高于增强T1加权成像（P<0.05）。在确定浸润深度方面，非增强T2加权成像的总体准确率为85%，增强T1加权成像为57%（P<0.05）。对于临床早期宫颈癌，使用传统SE序列时，非增强T2加权MR成像在确定浸润程度方面优于对比增强T1加权MR成像。
