Townsend D E, Fields G, McCausland A, Kauffman K
Intermountain Gynecologic Oncology Associates, Salt Lake City, Utah.
Obstet Gynecol. 1993 Sep;82(3):419-21.
To determine the cause and possible treatment of postmenopausal bleeding of 6 months' duration or longer.
One hundred ten women between the ages of 40-90 years with persistent postmenopausal bleeding were evaluated by diagnostic hysteroscopy and managed by operative hysteroscopy. All had endometrial sampling and/or office hysteroscopy before operative hysteroscopy.
A benign organic cause was noted in 95 cases (polyps in 42 and submucous fibroids in 53). Thirteen women had no significant disease and two had an early adenocarcinoma. Resection of the polyps or myomas without ablation was performed in 45 women, and all but one were satisfied with the results of treatment. Resection and ablation with performed in the remaining 50 patients with organic causes, and all but one were satisfied with the results. Twelve of 13 women without organic causes were satisfied with their treatment. The two adenocarcinomas were early lesions, grade 1 without invasion, and were managed by simple hysterectomy.
Diagnostic and operative hysteroscopy was effective in controlling postmenopausal bleeding of at least 6 months' duration. Almost 90% of the patients had either polyps or submucous fibroids as the primary cause of the bleeding. Resection alone and resection with ablation were equally effective in controlling the bleeding.
确定持续6个月及以上的绝经后出血的病因及可能的治疗方法。
对110例年龄在40至90岁之间、绝经后持续出血的女性进行诊断性宫腔镜检查,并通过手术宫腔镜进行治疗。所有患者在手术宫腔镜检查前均进行了子宫内膜取样和/或门诊宫腔镜检查。
95例发现良性器质性病因(42例为息肉,53例为黏膜下肌瘤)。13名女性无明显疾病,2名患有早期腺癌。45名女性进行了息肉或肌瘤切除但未进行消融,除1人外所有患者对治疗结果满意。其余50例有器质性病因的患者进行了切除和消融,除1人外所有患者对结果满意。13名无器质性病因的女性中有12名对治疗满意。这两名腺癌患者为早期病变,1级且无浸润,通过单纯子宫切除术治疗。
诊断性和手术性宫腔镜检查对控制持续至少6个月的绝经后出血有效。几乎90%的患者出血的主要原因是息肉或黏膜下肌瘤。单纯切除和切除加消融在控制出血方面同样有效。