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遗传性出血性毛细血管扩张症的神经学方面。两例报告。

Neurologic aspects of hereditary hemorrhagic telangiectasia. Report of two cases.

作者信息

Adams H P, Subbiah B, Bosch E P

出版信息

Arch Neurol. 1977 Feb;34(2):101-4. doi: 10.1001/archneur.1977.00500140055011.

Abstract

The several neurologic manifestations of hereditary hemorrhagic telangiectasia (HHT) may be caused by complications of pulmonary arteriovenous fistulae or associated central nervous system vascular malformations. The presence of skin and mucosal telangiectases should alert the clinician to the possibility of the disorder and in turn of its potential for associated neurologic disease, including cerebral hemorrhage and abscess. This report describes two cases and demonstrates that the clinical spectrum of HHT should be enlarged to include its admittedly rare, but serious, neurologic aspects.

摘要

遗传性出血性毛细血管扩张症(HHT)的多种神经学表现可能由肺动静脉瘘或相关的中枢神经系统血管畸形的并发症引起。皮肤和黏膜毛细血管扩张的存在应提醒临床医生注意该疾病的可能性,进而注意其发生相关神经疾病的可能性,包括脑出血和脑脓肿。本报告描述了两例病例,并表明HHT的临床谱应扩大,以纳入其虽公认罕见但严重的神经学方面。

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