Surzhikov S A, Diatkina N B
Bioorg Khim. 1993 Jul;19(7):722-8.
The condensation of 1, 2-di-O-acetyl-3-azido-3-deoxy-4-benzoyloxymethyl-1-5-O-benzoyl-bet a-D-ribofuranose with trimethylsilyl derivatives of N6-benzoyladenine, N4-acetylcytosine and uracil in the presence of stannic chloride led to the corresponding nucleosides. After deprotection with methanolic ammonia the azidonucleosides were reduced with PPh3 into 3'-amino-3'-deoxy-4'-hydroxymethynucleosides.
在氯化锡存在下，1,2 - 二 - O - 乙酰基 - 3 - 叠氮基 - 3 - 脱氧 - 4 - 苯甲酰氧基甲基 - 1,5 - O - 苯甲酰基 - β - D - 呋喃核糖与N6 - 苯甲酰腺嘌呤、N4 - 乙酰胞嘧啶和尿嘧啶的三甲基硅烷基衍生物缩合，得到相应的核苷。用甲醇氨脱保护后，叠氮核苷用三苯基膦还原为3'-氨基 - 3'-脱氧 - 4'-羟甲基核苷。
