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[人类沙门氏菌感染的发病机制]

[Pathogenesis of salmonella infections in humans].

作者信息

Sander J

机构信息

Staatliches Medizinaluntersuchungsamt, Hannover.

出版信息

Dtsch Tierarztl Wochenschr. 1993 Jul;100(7):283-5.

PMID:8375324
Abstract

The Public Health Laboratories in Germany have not only been isolating Salmonella species in general in increasing numbers during the last three years but observe especially a steep increase in the isolation rate of S. enteritidis. Epidemiological analyses indicate the involvement of chicken and eggs as frequent sources of the infectious agents. Although the clinical course of the disease in most cases is characterized by diarrhoea only, enteric fever and bacteremia do occur rather often. The latter applies especially to immunocompromised patients, to infants and to the elderly. The number of fatal cases is probably grossly underestimated because bacteriological tests are often not performed in old patients. The new epidemiological situation as well as the severe course of the disease in many cases lead physicians to strictly claim for food free of S. enteritidis.

摘要

在过去三年里,德国公共卫生实验室分离出的沙门氏菌数量总体呈上升趋势,尤其值得注意的是肠炎沙门氏菌的分离率急剧上升。流行病学分析表明,鸡肉和鸡蛋是常见的传染源。虽然大多数情况下该疾病的临床病程仅表现为腹泻,但肠热症和菌血症也较为常见。这在免疫功能低下的患者、婴儿和老年人中尤为明显。由于老年患者往往不进行细菌学检测,因此死亡病例的数量可能被严重低估。这种新的流行病学情况以及该疾病在许多病例中的严重病程,促使医生们严格要求提供不含肠炎沙门氏菌的食品。

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