[对1000例连续性急性脑血管病患者的分析。巴塞罗那中央医院-拉阿利安萨脑血管病登记处]

[An analysis of 1000 consecutive patients with acute cerebrovascular disease. The registry of cerebrovascular disease of La Alianza-Hospital Central of Barcelona].

作者信息

Arboix A, Massons J, Oliveres M, García L, Titus F

机构信息

Servicio de Neurología, La Alianza-Hospital Central, Barcelona.

出版信息

Med Clin (Barc). 1993 Sep 18;101(8):281-5.

PMID:8377532

Abstract

BACKGROUND

Registries of cerebral vascular disease (CVD) are useful in the study of the natural history of acute cerebrovascular disease (ACBD). Nonetheless there are few series which analyze the different stroke subtypes (SS) of CVD.

METHODS

A descriptive and comparative clinical analysis was performed of the different SS of CVD from the registry of CVD of the La Alianza-Central Hospital of Barcelona (Spain). A prospective study of 1,000 consecutive patients with ACVD admitted in the Neurology Department from 1986-1991 was carried out. The registry recommended by the Study Group of Cerebrovascular Diseases of the Sociedad Española de Neurología (SEN) were used and the stroke subtypes classified in agreement with the Glossary of Neurology of the SEN.

RESULTS

The mean age of the series was of 71 +/- 13 years with 537 patients being males. The frequency of the stroke subtypes in focal cerebral ischemia (FCI) was: thrombotic infarction 26%, lacunar infarction 16.9%, essential infarction 14.8%, cardioembolic infarction 12.4%, transient ischemic attacks 9% and infarction of unusual cause 3.5%. The frequency of the SS in cerebral hemorrhage (CH) was: intraparenchymatous hemorrhage 14.1%, subarachnoid hemorrhage 2.0%, subdural hematoma 1.2% and epidural hematoma 0.1%. Mortality of the series was 16.7% predominating in CH (28%) versus FCI (14%) (p < 0.00001). This was found to be greatest in cases of intraparenchymatous hemorrhage (31%) and in the cardioembolic infarction (28%) and lowest in the lacunar infarctions (0.6%).

CONCLUSIONS

The most common stroke subtypes were those of thrombotic infarctions, lacunar infarctions and intraparenchymal hemorrhages. Essential infarctions constitute 14.8% of acute cerebral vascular disease. The classification of cerebral vascular disease in its different subtypes is recommendable since this has prognostic and therapeutic implications.

摘要

背景

脑血管疾病（CVD）登记系统在急性脑血管疾病（ACBD）自然史研究中很有用。然而，很少有系列研究分析CVD的不同卒中亚型（SS）。

方法

对西班牙巴塞罗那中央医院阿利anza医院CVD登记系统中的不同CVD卒中亚型进行了描述性和比较性临床分析。对1986年至1991年神经内科收治的1000例连续ACVD患者进行了前瞻性研究。采用西班牙神经学会（SEN）脑血管疾病研究组推荐的登记系统，并根据SEN神经病学词汇表对卒中亚型进行分类。

结果

该系列患者的平均年龄为71±13岁，其中男性537例。局灶性脑缺血（FCI）中卒中亚型的频率为：血栓性梗死26%，腔隙性梗死16.9%，原发性梗死14.8%，心源性栓塞性梗死12.4%，短暂性脑缺血发作9%，不明原因梗死3.5%。脑出血（CH）中卒中亚型的频率为：脑实质内出血14.1%，蛛网膜下腔出血2.0%，硬膜下血肿1.2%，硬膜外血肿0.1%。该系列的死亡率为16.7%，CH（28%）高于FCI（14%）（p<0.00001）。这在脑实质内出血（31%）和心源性栓塞性梗死（28%）病例中最高，在腔隙性梗死（0.6%）中最低。