Figueras J, Valls C, Pamies J J, Benasco C, Sancho C, Rafecas A, Domínguez J, Torras J, Fabregat J, Baliellas C
Rev Esp Enferm Dig. 1993 Jan;83(1):21-5.
Transcatheter arterial chemoembolization with lipiodol and adriamycin was performed in 46 patients with hepatocellular carcinoma (HCC). In 27, this procedure was followed by selective arterial embolization using gelatin sponge particles. Surgical resection was carried out in 5 cases and 13 patients were transplanted (OLT). The aim of the study was to analyze the survival and degree of tumor necrosis. In the nonsurgical group the overall survival was 67% after 24 months in the OKUDA I stage, 31% after 20 months in the OKUDA II stage and 25% after 6 months in the OKUDA III stage. For the patients who underwent surgery, survival was 38% after 20 months in 5 patients who were resected and 72% after 24 months in 13 patients who were transplanted. Transcatheter arterial chemoembolization improves survival in patients who are not operated on, and can be used as a complementary treatment for patients who undergo surgery. A full tumor necrosis was observed in well encapsulated tumors.
对46例肝细胞癌(HCC)患者进行了经动脉化疗栓塞术,使用碘油和阿霉素。其中27例在该手术后采用明胶海绵颗粒进行选择性动脉栓塞。5例患者接受了手术切除,13例患者接受了肝移植(OLT)。本研究的目的是分析生存率和肿瘤坏死程度。在非手术组中,奥田I期患者24个月后的总生存率为67%,奥田II期患者20个月后的总生存率为31%,奥田III期患者6个月后的总生存率为25%。接受手术的患者中,5例接受切除的患者20个月后的生存率为38%,13例接受移植的患者24个月后的生存率为72%。经动脉化疗栓塞术可提高未接受手术患者的生存率,并可作为接受手术患者的辅助治疗。在包膜完整的肿瘤中观察到完全肿瘤坏死。