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抗惊厥药物诱发的甲状旁腺功能亢进的“棕色瘤”

"Brown tumor" of hyperparathyroidism induced with anticonvulsant medication.

作者信息

Campbell J E, Tam C S, Sheppard R H

出版信息

J Can Assoc Radiol. 1977 Mar;28(1):73-6.

PMID:838762
Abstract

A case history is presented of a 50-year-old epileptic receiving massive dose of phenobarbital and small doses of dilantin. Following a minor injury to her forearm a "brown tumor" of hyperparathyroidism and osteomalacia, both of which responded to vitamin D.A review of the literature is given; this is the second case reported which documents hyperparathyroidism under such circumstances, and the first to show radiographs of such changes. Radiologists should be aware of the possibility of these changes in patients on long-term anticonvulsants.

摘要

本文介绍了一名50岁癫痫患者的病例史,该患者正在接受大剂量苯巴比妥和小剂量苯妥英治疗。她的前臂受轻伤后出现了甲状旁腺功能亢进和骨软化的“棕色瘤”,两者对维生素D均有反应。文中给出了文献综述;这是第二例报告的在这种情况下记录甲状旁腺功能亢进的病例,也是第一例展示此类变化X光片的病例。放射科医生应意识到长期服用抗惊厥药的患者出现这些变化的可能性。

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