Miralles T G, Gosábez F, de Lera J, González L O, Penín C
Department of Pathology, Hospital Central de Asturias, Hospital Universitario, Oviedo, Spain.
Acta Cytol. 1993 Jul-Aug;37(4):499-502.
Fine needle aspiration biopsy (FNAB) is used routinely in the diagnosis of primary, benign, malignant and metastatic hepatic tumors. At our hospital, the staging protocol for small cell lung carcinomas and lymphomas requires biochemical determination of liver function, hepatic radionuclide analysis with 99Tc and abdominal echography (used also for FNAB guidance). We analyzed the effectiveness of these methods in 16 patients with a previous diagnosis of small cell lung carcinoma. They represented 22.5% of 71 patients on whom 142 FNABs of the liver were performed. Biochemistry was normal in 1 case of tumor and abnormal in 19 others in which all other determinations were normal. Echography was positive in 12 of the 16 cases; gammagraphy was abnormal in 11. FNAB of the liver therefore increased the sensitivity of the other procedures.
细针穿刺活检（FNAB）常用于原发性、良性、恶性及转移性肝肿瘤的诊断。在我院，小细胞肺癌和淋巴瘤的分期方案要求进行肝功能的生化测定、99Tc肝放射性核素分析以及腹部超声检查（也用于引导FNAB）。我们分析了这些方法对16例先前诊断为小细胞肺癌患者的有效性。他们占71例患者的22.5%，对这71例患者进行了142次肝脏FNAB。1例肿瘤患者生化指标正常，19例其他患者生化指标异常，而其他所有检查均正常。16例中有12例超声检查呈阳性；11例γ照相检查异常。因此，肝脏FNAB提高了其他检查方法的敏感性。
