Snow T R, McKeown P P
Department of Surgery, University of South Florida College of Medicine.
J Fla Med Assoc. 1993 Aug;80(8):545-8.
Even with heroic procedures, it is not yet possible to prevent cell death during a myocardial infarction; however, preconditioning has revealed an endogenous process capable of providing significant protection to the heart from such a fatal result. Mechanisms by which preconditioning operates have not yet been unraveled but its resolution has clear clinical significance.
即便采用大胆的治疗手段,在心肌梗死期间仍无法预防细胞死亡;然而,预处理已揭示出一种内源性过程,该过程能够为心脏提供显著保护,使其免遭这种致命后果。预处理发挥作用的机制尚未阐明,但其解决具有明确的临床意义。