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不育男性射精管梗阻的评估与治疗

Evaluation and treatment of ejaculatory duct obstruction in the infertile male.

作者信息

Meacham R B, Hellerstein D K, Lipshultz L I

机构信息

Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030.

出版信息

Fertil Steril. 1993 Feb;59(2):393-7. doi: 10.1016/s0015-0282(16)55683-0.

DOI:10.1016/s0015-0282(16)55683-0
PMID:8425637
Abstract

OBJECTIVE

To evaluate the role of ejaculatory duct obstruction as a cause for male factor infertility and review the treatment of this condition.

DESIGN

A retrospective study was carried out involving male patients diagnosed as having ejaculatory duct obstruction as a contributing cause for their subfertility.

SETTING

Patients were evaluated and treated through a university-based male infertility clinic.

PATIENTS, PARTICIPANTS: Patients were evaluated for the presence of ejaculatory duct obstruction if they suffered from decreased ejaculate volume, sperm density, and sperm motility but had normal physical examinations and otherwise normal laboratory evaluations.

INTERVENTIONS

Patients were treated by transurethral resection of the ejaculatory ducts.

MAIN OUTCOME MEASURES

Results of semen analysis and pregnancy rates.

RESULTS

An alteration in semen quality was achieved in 79% of patients after transurethral resection. An increase in sperm density or motility was achieved in 50%, whereas 29% showed an increase in ejaculate volume only. Pregnancy rate postoperatively was 29%.

CONCLUSIONS

Ejaculatory duct obstruction as a cause of male infertility is more common than was previously recognized, especially among nonazoospermic patients. In properly selected patients, transurethral resection of the ejaculatory ducts can result in marked improvement in semen quality with subsequent pregnancy.

摘要

目的

评估射精管梗阻作为男性因素不育病因的作用,并综述该病症的治疗方法。

设计

开展一项回顾性研究,纳入被诊断为射精管梗阻是其生育力低下的一个促成因素的男性患者。

地点

通过一所大学附属医院的男性不育诊所对患者进行评估和治疗。

患者、参与者:若患者精液量减少、精子密度降低且精子活力下降,但体格检查正常且其他实验室检查也正常,则对其进行射精管梗阻评估。

干预措施

对患者行经尿道射精管切除术。

主要观察指标

精液分析结果和妊娠率。

结果

经尿道切除术后,79%的患者精液质量得到改善。50%的患者精子密度或活力增加,而29%的患者仅精液量增加。术后妊娠率为29%。

结论

射精管梗阻作为男性不育的一个病因比之前认为的更为常见,尤其是在非无精子症患者中。在经过恰当选择的患者中,经尿道射精管切除术可使精液质量显著改善,随后实现妊娠。

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Evaluation and treatment of ejaculatory duct obstruction in the infertile male.不育男性射精管梗阻的评估与治疗
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