Harwerth R S, Smith E L, DeSantis L
College of Optometry, University of Houston, Texas 77204-6052.
Invest Ophthalmol Vis Sci. 1993 Jan;34(1):31-40.
Normative data on the systematic changes in visual sensitivity as a function of retinal eccentricity have provided the basis for efficient threshold strategies and data analysis routines for static perimetry. The standard methods of assessing visual field changes in patients also could be used for monkeys with experimentally induced ocular disorders if the normal visual fields of monkeys and humans were similar.
Normal visual field data from three rhesus monkeys were compared to data from eight human subjects using the standard threshold programs of the Humphrey Field Analyzer.
The experimental paradigm developed for these measurements provided excellent behavioral control for the monkeys, with reliability indices well within acceptable limits. The visual field data from monkeys were comparable to those from humans with respect to: (1) sensitivity as a function of stimulus field size; (2) the derived Statpac global indices; and (3) the variance of threshold measurements across the visual field.
The visual fields of monkeys and humans are similar, and the techniques of computerized perimetry may be applied to monkey subjects without significant modification.
作为视网膜偏心度函数的视觉敏感度系统变化的标准数据为静态视野检查的有效阈值策略和数据分析程序提供了基础。如果猴子和人类的正常视野相似，那么评估患者视野变化的标准方法也可用于患有实验性诱发眼部疾病的猴子。
使用汉弗莱视野分析仪的标准阈值程序，将三只恒河猴的正常视野数据与八名人类受试者的数据进行比较。
为这些测量开发的实验范式为猴子提供了出色的行为控制，可靠性指标完全在可接受范围内。猴子的视野数据在以下方面与人类的数据相当：（1）作为刺激视野大小函数的敏感度；（2）导出的Statpac全局指标；以及（3）整个视野阈值测量的方差。
猴子和人类的视野相似，计算机视野检查技术可在无需重大修改的情况下应用于猴子受试者。
