Dallera F, Gendarini A, Scanzi G
Servizio di Gastroenterologia ed Endoscopia Digestiva, Ospedale Maggiore, Lodi, Milano.
Recenti Prog Med. 1993 Jan;84(1):34-7.
The presence of Helicobacter was tested on a group with antral or duodenal ulcer with or without gastritis, versus a group without gastric or duodenal pathology. Furthermore an open trial was performed between omeprazole and colloidal bismuth subcitrate (CBS) on patients similarly affected by peptic disease. Although CBS did eliminate Helicobacter in more than a half of patients, what was not obtained by omeprazole, this result did not mean a better control of peptic disease: in fact the omeprazole was remarkably more active in our series on clinical and endoscopic ground, whether the Helicobacter was present or not, and further studies are required to assess the real significance of Helicobacter pylori in the above conditions.
在一组患有胃窦或十二指肠溃疡伴或不伴胃炎的患者中检测了幽门螺杆菌的存在情况,并与一组无胃或十二指肠病变的患者进行了对比。此外,还对患有消化性疾病的患者进行了奥美拉唑与枸橼酸铋钾(CBS)之间的开放试验。尽管CBS确实能使超过一半的患者根除幽门螺杆菌,而奥美拉唑则无法做到这一点,但这一结果并不意味着对消化性疾病有更好的控制:事实上,在我们的系列研究中,无论是否存在幽门螺杆菌,奥美拉唑在临床和内镜方面都表现得更为有效,因此需要进一步研究来评估幽门螺杆菌在上述情况下的实际意义。