类风湿性关节炎男性患者的髋部骨矿物质密度以及脊柱前后径和侧径的骨矿物质密度。低剂量皮质类固醇的影响。
Bone mineral density of the hip and of the anteroposterior and lateral dimensions of the spine in men with rheumatoid arthritis. Effects of low-dose corticosteroids.
作者信息
Garton M J, Reid D M
机构信息
Department of Rheumatology, City Hospital, Aberdeen, Scotland, United Kingdom.
出版信息
Arthritis Rheum. 1993 Feb;36(2):222-8. doi: 10.1002/art.1780360213.
OBJECTIVE
To assess bone mineral density (BMD) in men with steroid-treated rheumatoid arthritis (RA).
METHODS
Dual-energy x-ray absorptiometry (DXA) was used to measure BMD in 40 men with RA, 20 of whom were receiving low-dose corticosteroids (< or = 10 mg prednisolone daily), and in 20 healthy, age-matched male controls.
RESULTS
BMD was significantly reduced at the femoral neck and greater trochanter in both groups of RA patients, and at the spine from the anteroposterior dimension in the steroid-treated group.
CONCLUSION
Low-dose steroid therapy may induce excess axial osteopenia in men with RA.
目的
评估接受类固醇治疗的类风湿性关节炎（RA）男性患者的骨矿物质密度（BMD）。
方法
采用双能X线吸收法（DXA）测量40例RA男性患者的BMD，其中20例正在接受低剂量皮质类固醇治疗（每日泼尼松龙≤10 mg），并测量20名年龄匹配的健康男性对照者的BMD。
结果
两组RA患者的股骨颈和大转子处的BMD均显著降低，在接受类固醇治疗组中，脊柱前后径处的BMD也显著降低。
结论
低剂量类固醇治疗可能会导致RA男性患者出现过度的轴向骨质减少。
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