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乳腺癌。挑战与责任。

Breast cancer. Challenge and responsibility.

作者信息

Marchant D J

机构信息

Tufts University School of Medicine, Boston, Massachusetts.

出版信息

Cancer. 1993 Feb 15;71(4 Suppl):1518-22. doi: 10.1002/cncr.2820710417.

Abstract

The diagnosis and treatment of breast cancer has changed dramatically during the last quarter century, a fact perhaps not fully appreciated by many primary care physicians. Breast cancer presents a number of challenges for the obstetrician/gynecologist. The disease is common and the mortality rate is second only to lung cancer. The appropriate role for the obstetrician/gynecologist is one of surveillance, including taking a history and physical examination and selected diagnostic studies, and as a resource for patients, including a discussion of risk factors and treatment alternatives. Because of the increasing involvement of obstetrics and gynecology in molecular genetics and hormone interactions, basic research in genetic alterations and hormonal therapy directed toward decreasing morbidity from cardiovascular disease and osteoporosis is recommended.

摘要

在过去的四分之一个世纪里,乳腺癌的诊断和治疗发生了巨大变化,这一事实或许并未得到许多初级保健医生的充分认识。乳腺癌给妇产科医生带来了诸多挑战。这种疾病很常见,死亡率仅次于肺癌。妇产科医生的恰当角色之一是进行监测,包括问诊、体格检查以及选择诊断性检查,同时作为患者的资源提供者,包括讨论风险因素和治疗选择。由于妇产科在分子遗传学和激素相互作用方面的参与日益增加,建议开展针对减少心血管疾病和骨质疏松症发病率的基因改变和激素治疗的基础研究。

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