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[白血病孕妇接受持续细胞抑制治疗后成功分娩]

[Successful delivery following continuous cytostatic therapy of a leukemic pregnant women].

作者信息

Szántó F, Kovács L

机构信息

Szent-Györgyi Albert Orvostudományi Egyetem Szülészeti és Nögyógyászati Klinika, Szeged.

出版信息

Orv Hetil. 1993 Mar 7;134(10):527-9.

PMID:8446405
Abstract

The authors report about a successful labour and delivery after pregnancy with chronic myeloid leukemia treated with hydroxyurea. The haematological state of the mother could be well balanced with this cytostatic drug. The fetus was in a good condition during the whole pregnancy. At term a healthy newborn delivered with no signs of malformation or haematological disease. At a follow up visit 6 weeks after delivery the state of the mother and the newborn was satisfactory. The incidence of leukemia and pregnancy is rare. The creation of a central registry to pool experiences and data would help define optimum treatment regimens for this group of patients. A close cooperation among haematologist, obstetrician and pediatrician is emphasized.

摘要

作者报告了一例慢性粒细胞白血病患者在孕期使用羟基脲治疗后成功分娩的病例。母亲的血液学状态通过这种细胞毒性药物得到了良好的平衡。整个孕期胎儿状况良好。足月时分娩出一名健康新生儿,无畸形或血液系统疾病迹象。产后6周的随访显示,母亲和新生儿的状况令人满意。白血病与妊娠的发生率很低。建立一个中央登记处来汇总经验和数据,将有助于为这组患者确定最佳治疗方案。强调血液科医生、产科医生和儿科医生之间要密切合作。

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