蛋白酶与淋巴细胞细胞毒性杀伤机制。
Proteases and lymphocyte cytotoxic killing mechanisms.
作者信息
Hudig D, Ewoldt G R, Woodard S L
机构信息
Department of Microbiology, School of Medicine, University of Nevada, Reno 89557-0046.
出版信息
Curr Opin Immunol. 1993 Feb;5(1):90-6. doi: 10.1016/0952-7915(93)90086-8.
PMID:8452680
Abstract
A subfamily of serine proteases is uniquely expressed by cytotoxic natural killer lymphocytes and T cells. Protease cleavage of different natural substrates is now implicated in the cytotoxic mechanisms of target cell membrane pore formation, DNA fragmentation and cytostasis.
摘要
丝氨酸蛋白酶的一个亚家族由细胞毒性自然杀伤淋巴细胞和T细胞独特地表达。不同天然底物的蛋白酶切割现在与靶细胞膜孔形成、DNA片段化和细胞生长停滞的细胞毒性机制有关。
Zotero 插件