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11C-L-蛋氨酸和PET诊断复发性少突胶质细胞瘤:病例报告

Recurrent oligodendroglioma diagnosed with 11C-L-methionine and PET: a case report.

作者信息

Viader F, Derlon J M, Petit-Taboué M C, Shishido F, Hubert P, Houtteville J P, Courtheoux P, Chapon F

机构信息

Department of Neurology, University Hospital of Caen, France.

出版信息

Eur Neurol. 1993;33(3):248-51. doi: 10.1159/000116947.

Abstract

A benign oligodendroglioma was removed in a young patient who had temporal epileptic seizures. He then became free of any fit until 15 months after the operation, when he developed seizures progressively less controlled by therapy. All investigations were normal (including CT scan and MRI) except a PET study which showed a high uptake of 11C-L-methionine in the area of the previous tumor. The second operation revealed that this area was indeed a tumor recurrence. We briefly discuss the potential usefulness of PET for the follow-up of low grade gliomas.

摘要

一名患有颞叶癫痫发作的年轻患者切除了良性少突胶质细胞瘤。术后他一直未再发作,直到术后15个月,癫痫发作逐渐变得难以通过治疗控制。除了PET研究显示先前肿瘤区域有11C-L-蛋氨酸的高摄取外,所有检查(包括CT扫描和MRI)均正常。第二次手术显示该区域确实是肿瘤复发。我们简要讨论了PET在低级别胶质瘤随访中的潜在用途。

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