Melki J P, Fermand M, Riche M C, Lazareth I, Priollet P, Cormier J M
Service de Radiologie et d'Imagerie médicale, Hôpital Saint-Joseph, Paris.
J Mal Vasc. 1993;18(1):37-41.
Results are reported of a retrospective analysis of transluminal angioplasty (TLA) interventions in 20 diabetic patients, 16 men and 4 women, mean age 56 years (range 32 to 82 years), with 24 dilated lesions, 16 patients having insulin-dependent diabetes. In 12 cases the lesions were at the intermittent claudication stage, trophic lesions being present in 8 cases. Stenotic lesions were iliac (12 cases), superficial femoral (2 cases), popliteal (6 cases) and tibial (4 cases). One patient developed an acute occlusion following popliteal-anterior tibial recanalization, the only direct complication of the angioplasty. Angiography showed immediate satisfactory results in 22 of the 24 dilated lesions. Functional and hemodynamic improvement was a constant finding in patients with intermittent claudication, trophic lesions being healed in 4 cases (50%) the other patient showing either no change or requiring an unavoidable amputation (2 cases). These overall findings suggest that at the intermittent claudication stage no differences exist in the results of TLA when compared with a non diabetic population; inversely, in the presence of trophic disorders, the local conditions (distal bed, infection, gangrene) interfere considerably in the course of the dilatation. Transluminal angioplasty should therefore be carried out as early as possible in diabetics; arteriography should be performed as soon as even minimal claudication appears and, a fortiori, even at the onset of a trophic lesion.
报告了对20例糖尿病患者进行腔内血管成形术(TLA)干预的回顾性分析结果。患者中16例为男性,4例为女性,平均年龄56岁(范围32至82岁),有24处扩张病变,16例患者为胰岛素依赖型糖尿病。12例病变处于间歇性跛行阶段,8例有营养性病变。狭窄病变位于髂动脉(12例)、股浅动脉(2例)、腘动脉(6例)和胫动脉(4例)。1例患者在腘动脉-胫前动脉再通后发生急性闭塞,这是血管成形术唯一的直接并发症。血管造影显示24处扩张病变中有22处立即取得了满意的结果。间歇性跛行患者持续出现功能和血流动力学改善,4例(50%)营养性病变愈合,另外2例患者无变化或需要进行不可避免的截肢。这些总体结果表明,在间歇性跛行阶段,与非糖尿病人群相比,TLA的结果没有差异;相反,在存在营养障碍时,局部情况(远端床、感染、坏疽)在扩张过程中会产生相当大的干扰。因此,糖尿病患者应尽早进行腔内血管成形术;一旦出现哪怕是轻微的跛行,甚至在营养性病变出现之初,就应进行动脉造影。