与双侧基底神经节病变相关的反射性眼睑痉挛。

Reflex blepharospasm associated with bilateral basal ganglia lesion.

作者信息

Larumbe R, Vaamonde J, Artieda J, Zubieta J L, Obeso J A

机构信息

Department of Neurology, University of Navarra Medical School, Pamplona, Spain.

出版信息

Mov Disord. 1993 Apr;8(2):198-200. doi: 10.1002/mds.870080215.

DOI:10.1002/mds.870080215

PMID:8474489

Abstract

A patient with a bilateral striatal lesion secondary to anoxia presented reflex blepharospasm associated with parkinsonism and dystonia in the limbs. The blink reflex excitability curve was enhanced and the R-2 response prolonged as in patients with essential blepharospasm. The findings in this patient support the notion that blepharospasm may be secondary to basal ganglia dysfunction through abnormal facilitation of reticular formation neurons controlling facial nucleus motoneuron excitability.

摘要

一名因缺氧继发双侧纹状体病变的患者出现了与帕金森病和肢体肌张力障碍相关的反射性眼睑痉挛。眨眼反射兴奋性曲线增强，R-2反应延长，与特发性眼睑痉挛患者的情况相同。该患者的研究结果支持这样一种观点，即眼睑痉挛可能是由于控制面神经核运动神经元兴奋性的网状结构神经元异常易化，继发于基底神经节功能障碍。