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[炎症性和恶性疾病中的免疫闪烁显像。抗白细胞和抗肿瘤抗体]

[Immunoscintigraphy in inflammatory and malignant diseases. anti-leukocyte and anti-tumor antibodies].

作者信息

Kramer W, Baum R P, Hör G, Jonas D

机构信息

Klinik für Urologie, Johann-Wolfgang-Goethe-Universität, Frankfurt/Main.

出版信息

Urologe A. 1993 Mar;32(2):108-14.

PMID:8475608
Abstract

Antibody-labelled granulocytes, antigranulocyte antibodies and radiolabelled immunoglobulin can reliably visualize foci of infection; their use in urologic inflammatory disorders is rare. In the diagnosis of urologic tumours anti-CEA immunoscintigraphy of urinary bladder cancer seems to be superior to conventional imaging techniques in sensitivity and specificity. Experience with immunoscintigraphy in non-seminomatous germ cell tumours and prostate cancer are limited; immunoscintigraphy of renal cell cancer is still in the experimental stage in clinical medicine.

摘要

抗体标记的粒细胞、抗粒细胞抗体和放射性标记的免疫球蛋白能够可靠地显示感染病灶;它们在泌尿系统炎性疾病中的应用很少见。在泌尿系统肿瘤的诊断中,膀胱癌的抗癌胚抗原免疫闪烁成像在敏感性和特异性方面似乎优于传统成像技术。非精原细胞性生殖细胞肿瘤和前列腺癌免疫闪烁成像的经验有限;肾细胞癌的免疫闪烁成像在临床医学中仍处于实验阶段。

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