氨鲁米特（AG）与氢化可的松（HC）用于骨转移的回顾性研究
Aminoglutethimide (AG) and hydrocortisone (HC) in bone metastases: a retrospective study.
作者信息
Bonneterre J, Adenis A, Pion J M, Cambier L, Kamus E, Hecquet B
机构信息
Centre Oscar Lambret, Lille, France.
出版信息
J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):693-6. doi: 10.1016/0960-0760(93)90284-4.
PMID:8476786
Abstract
The response rate in bone metastases in 57 patients treated with aminoglutethimide and hydrocortisone was retrospectively assessed. All the X-rays were reviewed by two senior radiologists. A response was observed in 23% of the patients, a stabilization in 32%. The survival was not different whether a response or stabilization was observed. Conversely, survival was significantly worse in patients who experienced a progressive disease.
摘要
回顾性评估了57例接受氨鲁米特和氢化可的松治疗的骨转移患者的缓解率。所有X线片均由两位资深放射科医生复查。23%的患者出现缓解，32%病情稳定。无论观察到缓解还是病情稳定，患者的生存率并无差异。相反，疾病进展的患者生存率显著更差。
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