Kino T
Department of Internal Medicine, Kobe Teishin Hospital.
Nihon Rinsho. 1993 Mar;51(3):765-70.
Allergic bronchopulmonary aspergillosis (ABPA) is an allergic disease caused by viable Aspergillus in a relatively large bronchus and by the type I and type III allergies against the fungus. The clinical findings are characterized by recurrent pyrexial attacks (fever, cough and mucopurulent sputum containing mucous plugs, numerous eosinophils and the fungus), radiological evidence of recurrent collapse and consolidation in different areas of the lung, a blood eosinophilia and elevated serum IgE levels. Fungi other than Aspergillus may cause similar allergological diseases. Therefore, they should be call allergic bronchopulmonary fungal diseases (ABPF). Many diagnostic criteria of the disease have been proposed by many different authors, but, a return should be made to the original report by Hinson et al, 1952.
变应性支气管肺曲霉病(ABPA)是一种由相对较大支气管内的活曲霉以及针对该真菌的Ⅰ型和Ⅲ型过敏反应所引起的变应性疾病。其临床特征为反复发热发作(发热、咳嗽以及含有黏液栓、大量嗜酸性粒细胞和真菌的黏液脓性痰)、肺部不同区域反复出现肺不张和实变的影像学证据、血液嗜酸性粒细胞增多以及血清IgE水平升高。除曲霉之外的真菌也可能引起类似的变应性疾病。因此,它们应被称为变应性支气管肺真菌病(ABPF)。许多不同的作者提出了该疾病的多种诊断标准,但是,应该回归到Hinson等人1952年的原始报告。