Shibuya T
Department of Parasitology, Teikyo University School of Medicine.
Nihon Rinsho. 1993 Mar;51(3):825-31.
The increase of eosinophiles in peripheral blood and in the lesion is characteristic feature of many parasitic diseases. Those parasites which invade host organs generally cause eosinophilia of high degree. Thus, zoonotic parasites belonging to genuses gnathostoma, paragonimus and angiostrongylus etc. bring about continuous hypereosinophilic response due to lasting larval migration, but in contrast, those which migrate temporarily during the developmental stage in the host, cause transient eosinophilia, as in Loeffler's syndrome, due to round worms. In contrast, those parasites which live in the luminal organ and never invade tissues, may not cause eosinophilia. The variety of patterns in eosinophile response is outlined together with some clinical data.
外周血和病变部位嗜酸性粒细胞增多是许多寄生虫病的特征性表现。那些侵入宿主器官的寄生虫通常会引起高度嗜酸性粒细胞增多。因此，属于颚口线虫属、肺吸虫属和广州管圆线虫属等的人畜共患寄生虫，由于幼虫持续移行，会导致持续性嗜酸性粒细胞增多反应，但相比之下，那些在宿主体内发育阶段暂时移行的寄生虫，如蛔虫引起的吕弗勒综合征，则会导致短暂性嗜酸性粒细胞增多。相反，那些生活在管腔器官且从不侵入组织的寄生虫，可能不会引起嗜酸性粒细胞增多。本文概述了嗜酸性粒细胞反应的各种模式以及一些临床数据。
