下肢基底细胞癌中既往存在疾病的意义。
Significance of pre-existent conditions in basal cell carcinoma on the lower extremities.
作者信息
Nogita T, Kamikawa T, Kawashima M
机构信息
Department of Dermatology, Tokyo Women's Medical College, Japan.
出版信息
Int J Dermatol. 1993 May;32(5):350-3. doi: 10.1111/j.1365-4362.1993.tb01471.x.
BACKGROUND
Basal cell carcinoma (BCC) rarely appears on the lower extremities; over 85% appear on the head and neck.
CASE REPORTS
Five patients had BCC on the lower extremity. Histologically, this was of the superficial type. One patient developed a lesion of actinic keratosis.
RESULTS
The presence of pre-existent cutaneous changes of BCC arising on the lower extremities was studied. Among 40 tumors reported in Japan, 10 cases (25%) had pre-existent cutaneous changes. This value is significantly higher than those of BCC over the whole body in both Japanese and Caucasian.
CONCLUSIONS
Pre-existent cutaneous changes, thus, are thought to be a possible etiologic factor in the pathogenesis of BCC on the lower extremities.
背景
基底细胞癌（BCC）很少出现在下肢；超过85%出现在头颈部。
病例报告
5例患者下肢患有基底细胞癌。组织学上，属于浅表型。1例患者出现了光化性角化病病变。
结果
对下肢出现的基底细胞癌先前存在的皮肤变化情况进行了研究。在日本报告的40例肿瘤中，10例（25%）有先前存在的皮肤变化。该数值显著高于日本人和高加索人全身基底细胞癌的相应数值。
结论
因此，先前存在的皮肤变化被认为是下肢基底细胞癌发病机制中一个可能的病因。
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