Karesh J W, Nirankari V S, Hameroff S B
Department of Ophthalmology, University of Maryland, Baltimore.
Ophthalmology. 1993 Jun;100(6):883-9.
Eighteen patients with chronic ocular irritation were examined over a 3-year period. All patients demonstrated papillary conjunctivitis and, occasionally, tarsal ulcers. Six also had floppy eyelid syndrome. Underlying every patient's symptoms was the overriding or imbrication of a lax upper eyelid on an often equally lax lower eyelid, allowing lower eyelid lashes to chronically rub the upper eyelid tarsal conjunctiva.
Chronic ocular irritation in five patients was managed with ocular lubricants. Two of these patients had floppy eyelid syndrome and required nightime shielding for nocturnal eyelid eversion. Thirteen patients underwent eyelid surgery to correct the overriding upper eyelid. Surgical procedures included full-thickness upper eyelid wedge resection, lateral canthal tendon plication, and lower eyelid horizontal shortening, using a tarsal strip procedure.
Follow-up averaged 2.5 years. Symptomatology was adequately controlled in all patients. In addition to the five patients who received medical treatment for their symptoms, two with complicated ocular problems required continued ocular lubrication after surgery. Seven patients were successfully treated with eyelid shortening procedures and lateral canthal tendon plication. The remaining six patients underwent a variety of additional eyelid surgeries. All patients undergoing surgery had complete resolution of eyelid imbrication.
Eyelid imbrication is a previously unrecognized cause of chronic ocular irritation. In this condition, eyelid laxity causes the upper eyelid to override the lower eyelid, allowing the lower eyelid to chronically rub and chafe the upper eyelid tarsal conjunctiva. In some cases, symptoms can be managed medically. More often, surgical intervention is required to correct eyelid laxity and prevent overriding of the upper eyelid.
在3年的时间里对18例慢性眼部刺激患者进行了检查。所有患者均表现为乳头性结膜炎,偶尔还伴有睑板溃疡。其中6例还患有眼睑松弛综合征。每位患者症状的根本原因是松弛的上眼睑覆盖或重叠在同样松弛的下眼睑上,导致下眼睑睫毛长期摩擦上眼睑睑板结膜。
5例患者的慢性眼部刺激采用眼部润滑剂治疗。其中2例患有眼睑松弛综合征,需要夜间使用眼罩防止夜间眼睑外翻。13例患者接受了眼睑手术以纠正上眼睑覆盖问题。手术方法包括全层上眼睑楔形切除术、外眦韧带折叠术以及采用睑板条手术的下眼睑水平缩短术。
随访平均2.5年。所有患者的症状均得到充分控制。除了5例接受症状治疗的患者外,2例患有复杂眼部问题的患者术后仍需要持续使用眼部润滑剂。7例患者通过眼睑缩短手术和外眦韧带折叠术成功治愈。其余6例患者接受了各种额外的眼睑手术。所有接受手术的患者眼睑重叠问题均完全解决。
眼睑重叠是慢性眼部刺激的一个此前未被认识到的原因。在这种情况下,眼睑松弛导致上眼睑覆盖下眼睑,使下眼睑长期摩擦和擦伤上眼睑睑板结膜。在某些情况下,症状可以通过药物治疗。更多时候,需要手术干预来纠正眼睑松弛并防止上眼睑覆盖。