Smith J R, King D W
Section of Neurosurgery, Medical College of Georgia, Augusta 30912.
J Med Assoc Ga. 1993 Apr;82(4):177-80.
In the United States, there are approximately 75,000 patients with medically intractable epilepsy of focal origin who are candidates for ablative surgery. Currently, about 1500 epilepsy operations are performed per year in the United States. Candidates for ablative surgery (i.e., removal of epileptogenic tissue) are those with a reasonable chance of reduction in seizure frequency and improvement of overall lifestyle. The epileptogenic tissue must be localized preoperatively by either non-invasive or invasive recordings, or by imaging studies (e.g., MRI). Nearly 60% of all patients who undergo resection of a temporal or extra-temporal seizure focus become seizure free, and about 70% have no seizures or only rare ones. The most commonly performed operation is anterior temporal lobectomy. This update article will also review the results of other epilepsy operations which are currently performed--hemispherectomy, corpus callosotomy, and multiple subpial transection.
在美国，约有75000名患有局灶性起源的药物难治性癫痫患者适合进行切除性手术。目前，美国每年约进行1500例癫痫手术。适合切除性手术（即切除致痫组织）的患者是那些癫痫发作频率有合理机会降低且整体生活方式能得到改善的人。致痫组织必须在术前通过非侵入性或侵入性记录，或通过影像学检查（如磁共振成像）来定位。在所有接受颞叶或颞外癫痫病灶切除的患者中，近60%的患者癫痫发作停止，约70%的患者无癫痫发作或仅有罕见发作。最常进行的手术是前颞叶切除术。这篇更新文章还将回顾目前进行的其他癫痫手术的结果——大脑半球切除术、胼胝体切开术和多处软膜下横切术。
