Cohen M M, Dangleis K
Videoscopic Surgery Center, Rose Medical Center, Denver, CO.
J Laparoendosc Surg. 1993 Apr;3(2):93-7. doi: 10.1089/lps.1993.3.93.
The first 26 attempted laparoscopic appendectomies for the clinical diagnosis of acute appendicitis were compared with an age and sex matched control group of patients randomly selected from those operated on for acute appendicitis during the previous 6 month period. Both groups were comparable in terms of severity of disease, absolute white count, previous surgery, and co-morbidity. The mean operative time for the laparoscopic appendectomy group was 73 min vs 36 min for the open group (p < 0.001), but the morbidity (12% vs 38%) was significantly less (p < 0.01). The length of stay was shorter (2.8 vs 3.4 days) but this failed to achieve statistical significance. The time to full recovery was significantly (p < 0.01) shorter (11.1 vs 23.7 days). Hospital charges for laparoscopic appendectomy were higher (but not significantly) than for open appendectomy. The results of this study confirm that laparoscopic appendectomy is a safe and effective alternative to open appendectomy which results in a more rapid return to full activity but incurs higher hospital charges. The overall cost effectiveness of laparoscopic appendectomy should be even greater than that of open appendectomy.
将首次尝试的26例因临床诊断为急性阑尾炎而行腹腔镜阑尾切除术的患者,与在前6个月期间因急性阑尾炎接受手术的患者中随机选取的年龄和性别匹配的对照组进行比较。两组在疾病严重程度、白细胞绝对值、既往手术史和合并症方面具有可比性。腹腔镜阑尾切除术组的平均手术时间为73分钟,而开放手术组为36分钟(p < 0.001),但腹腔镜阑尾切除术组的发病率(12%对38%)显著更低(p < 0.01)。住院时间更短(2.8天对3.4天),但未达到统计学显著性。完全恢复时间显著更短(p < 0.01)(11.1天对23.7天)。腹腔镜阑尾切除术的住院费用高于开放阑尾切除术(但不显著)。本研究结果证实,腹腔镜阑尾切除术是开放阑尾切除术的一种安全有效的替代方法,可使患者更快恢复到完全活动状态,但住院费用更高。腹腔镜阑尾切除术的总体成本效益应高于开放阑尾切除术。