Cofta S, Lowicki Z, Młynarczyk W
Kliniki Pneumonologii Akademii Medycznej w Poznaniu.
Pneumonol Alergol Pol. 1995;63(7-8):407-9.
The acetylation phenotype is genetically predetermined. It might influence the development of several diseases. It can also be changed by the active process of diseases. The aim of the study was to determinate the acetylation phenotype of individuals with lung cancer. Sulfadimidine acetylation study was undertaken in 30 patients with lung cancer and 30 individuals of control group. There is a significantly higher proportion of slow acetylators in the group of patients with lung cancer than in those without the disease.
乙酰化表型由基因预先决定。它可能影响多种疾病的发展。它也可能因疾病的活动过程而改变。本研究的目的是确定肺癌患者的乙酰化表型。对30例肺癌患者和30例对照组个体进行了磺胺二甲嘧啶乙酰化研究。肺癌患者组中慢乙酰化者的比例显著高于无病组。