Allsop E, Innes P, Jackson M, Cunliffe M
Alder Hey Children's Hospital Trust, Liverpool, UK.
Paediatr Anaesth. 1995;5(1):47-51. doi: 10.1111/j.1460-9592.1995.tb00240.x.
We have assessed the ease of insertion of the Brain Laryngeal Mask Airway (LMA) after induction of anaesthesia with propofol in 60 healthy unpremedicated children aged between four and nine years. Patients were randomly allocated into three groups: group A = propofol 2.5 mg.kg-1; group B = propofol 3 mg.kg-1 and group C = propofol 3.5 mg.kg-1. Propofol was mixed with lignocaine 0.5 mg.kg-1. Insertion conditions were assessed subjectively as good, acceptable, unacceptable or impossible. Insertion of the LMA was possible in all patients. Good and acceptable conditions were obtained in 35%, 70% and 95% in groups A, B, and C respectively (P < 0.0001). There was no statistically significant inter group variation in systolic and diastolic arterial pressure or in heart rate for five min after induction. All measured cardiovascular changes were considered to be clinically insignificant in healthy children. We conclude it is safe and effective to insert a LMA immediately after induction of anaesthesia with propofol 3.5 mg.kg-1.
我们评估了在60名年龄在4至9岁、未使用术前药的健康儿童中，使用丙泊酚诱导麻醉后插入脑喉罩气道（LMA）的难易程度。患者被随机分为三组：A组 = 丙泊酚2.5mg·kg⁻¹；B组 = 丙泊酚3mg·kg⁻¹；C组 = 丙泊酚3.5mg·kg⁻¹。丙泊酚与0.5mg·kg⁻¹的利多卡因混合。插入条件主观评估为良好、可接受、不可接受或不可能。所有患者均成功插入LMA。A组、B组和C组分别有35%、70%和95%的患者获得了良好和可接受的条件（P < 0.0001）。诱导后5分钟内，收缩压、舒张压和心率在组间无统计学显著差异。所有测量的心血管变化在健康儿童中被认为在临床上无显著意义。我们得出结论，在使用3.5mg·kg⁻¹丙泊酚诱导麻醉后立即插入LMA是安全有效的。
