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KNOTTED1同源域蛋白及其mRNA通过胞间连丝的选择性运输。

Selective trafficking of KNOTTED1 homeodomain protein and its mRNA through plasmodesmata.

作者信息

Lucas W J, Bouché-Pillon S, Jackson D P, Nguyen L, Baker L, Ding B, Hake S

机构信息

Section of Plant Biology, University of California, Davis 95616, USA.

出版信息

Science. 1995 Dec 22;270(5244):1980-3. doi: 10.1126/science.270.5244.1980.

DOI:10.1126/science.270.5244.1980
PMID:8533088
Abstract

Plasmodesmata are intercellular organelles in plants that establish cytoplasmic continuity between neighboring cells. Microinjection studies showed that plasmodesmata facilitate the cell-to-cell transport of a plant-encoded transcription factor, KNOTTED1 (KN1). KN1 can also mediate the selective plasmodesmal trafficking of kn1 sense RNA. The emerging picture of plant development suggests that cell fate is determined at least in part by supracellular controls responding to cellular position as well as lineage. One of the mechanisms that enables the necessary intercellular communication appears to involve transfer of informational molecules (proteins and RNA) through plasmodesmata.

摘要

胞间连丝是植物细胞间的细胞器,可在相邻细胞间建立细胞质连续性。显微注射研究表明,胞间连丝有助于植物编码的转录因子KNOTTED1(KN1)在细胞间运输。KN1还能介导kn1正义RNA的选择性胞间连丝运输。植物发育的新情况表明,细胞命运至少部分由响应细胞位置以及谱系的超细胞控制决定。实现必要的细胞间通讯的机制之一似乎涉及信息分子(蛋白质和RNA)通过胞间连丝的转移。

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