Norethisterone enantate in the treatment of premenstrual syndrome.

The aim of this prospective study was to assess whether norethisterone enantate can be recommended for use in patients with premenstrual syndrome (PMS) who also require effective contraception. The subjects were 20 patients with severe PMS who required effective contraception. Premenstrual symptom scores on norethisterone enantate and oral contraceptives were compared. Significantly fewer and less severe symptoms were experienced by patients on norethisterone enantate than those on oral contraceptives. Norethisterone enantate can therefore be recommended for use in patients with PMS who also require effective contraception.